Study to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
Information and news on study funded by National Institute of Neurological Disorders and Stroke (NINDS) helps explain why newborn brain responds differently to anticonvulsant medications.